[Neurophysiologic evaluation of cognitive disorders in patients with epilepsy]

Aiming to evaluate cognitive disorders in patients with epilepsy examinations were performed using WB scale and event related potentials (ERP) as well as in the control group of healthy volunteers. The study involved 12 patients with epilepsy aging from 15 to 65 years and duration of the disease from 5 to 21 years, 8 males and 4 females: 9 patients received monotherapy and 3 polytherapy. Auditory ERP were studied by averaging 128 expected responses. Recording electrodes were placed by the 10-20 system at sites Fz, C3, Cz, C4, Pz, P4. After recording of the repeated responses the determination of latency of P-300 wave and N2-P3 amplitude were performed. Prolongation of latency of P-300 wave and increased amplitude were recorded in patients with polytherapy and longer duration of the disease. It has been concluded that in patients with chronic epilepsy treated by polytrauma there are changes of the basic characteristics of the parameters of of the cognitive evoked responses.