Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Polymerized vesicles containing molecular recognition sites.

Markus Biesalski1, Raymond Tu, Matthew V Tirrell

  • 1Institute for Microsystem Technology (IMTEK), Department of Chemistry and Physics of Interfaces, University of Freiburg, 79085 Freiburg, Germany. biesalsk@imtek.de

Langmuir : the ACS Journal of Surfaces and Colloids
|June 15, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Composite biomaterials of polyelectrolyte complex micelle nanoparticles in hyaluronic acid gels enable local, targeted miR-92a inhibition and enhanced angiogenesis in diabetic wound repair.

Journal of controlled release : official journal of the Controlled Release Society·2026
Same author

Effect of Polymer Structure on the Thermodynamics of Polyelectrolyte Complex Micelle Formation.

Macromolecules·2026
Same author

Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles.

Cell reports. Medicine·2026
Same author

Peptide-reinforced, photocrosslinkable PEG-based hydrogels.

RSC applied polymers·2026
Same author

Precision mRNA Nanomedicine for Targeted Vascular Therapies in ARDS and Atherosclerosis.

bioRxiv : the preprint server for biology·2026
Same author

Polyelectrolyte complex micelles embedded in hyaluronic acid gels enable local, targeted miR-92a inhibition to accelerate diabetic wound repair.

bioRxiv : the preprint server for biology·2025
Same journal

Immobilization of Ytterbium via Polyphenol Chemistry on Implant Materials for Enhanced Cytocompatibility and Antibacterial Properties.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Electrochemical Oxidation Strategy for Integrated CO<sub>2</sub> Capture and Conversion.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Probing Molecular Structural Changes of Buried Interfaces between Polyethylene and Nylon in Polymer Thin Films after Stretching.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Charge Dependence of Local Hydration Dynamics in Poly(Acrylic Acid) Solutions.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Amphiphilic Lubricants Linked by Hydrogen Bonds Achieve Superlubricity and Enhance Water/Oil Tribological Properties.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Spin Dewetting of Ultrathin Polymer Films.

Langmuir : the ACS journal of surfaces and colloids·2026
See all related articles

New polymeric vesicles made from diacetylenic peptide amphiphiles offer label-free protein detection. UV polymerization creates vesicles with chromatic responses, enabling visualization of molecular interactions without labels.

Area of Science:

  • Supramolecular Chemistry
  • Materials Science
  • Biotechnology

Background:

  • Peptide amphiphiles are self-assembling molecules with potential in nanotechnology.
  • Polymerization of diacetylenic amphiphiles can yield responsive materials.
  • Label-free detection methods are crucial for studying biomolecular interactions.

Purpose of the Study:

  • To develop novel polymeric vesicles from diacetylenic peptide amphiphiles.
  • To investigate the chromatic response of these vesicles upon UV polymerization.
  • To demonstrate their utility in label-free protein detection.

Main Methods:

  • Synthesis of diacetylenic peptide amphiphiles.
  • Self-assembly into vesicles.
  • UV-induced polymerization.

Related Experiment Videos

  • Spectroscopic analysis of chromatic changes.
  • Protein binding assays.

    • Main Results:

    • Vesicles formed successfully from diacetylenic peptide amphiphiles.
    • UV polymerization resulted in stable polymeric vesicles.
    • Polymeric vesicles exhibited distinct chromatic responses.
    • These chromatic changes correlated with protein binding events.

    Conclusions:

    • Diacetylenic peptide amphiphile vesicles can be polymerized to create responsive nanomaterials.
    • The chromatic response allows for label-free detection of protein interactions.
    • This platform holds promise for biosensing applications.