Related Experiment Video
Updated: Aug 17, 2026

11:26
Ecotoxicological Method with Marine Bacteria Vibrio anguillarum to Evaluate the Acute Toxicity of Environmental Contaminants
Published on: May 26, 2017
Bioavailability and ecotoxicity of nickel: effects of water quality characteristics
B T Bossuyt1, B J Cornelis, C R Janssen
1Ghent University, Laboratory of Environmental Toxicology and Aquatic Ecology, J. Plateaustraat 22, B-9000 Ghent, Belgium.
Abstract
No abstract available in PubMed .
Related Concept Videos
Toxicity Testing in Animals
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Toxicokinetics: Overview
Studies that assess how a drug is absorbed, distributed, metabolized, and excreted (ADME) at toxic doses are termed toxicokinetics. Understanding toxicokinetics helps predict adverse drug reactions (ADRs) and manage toxicity in humans.Toxicokinetics differs from pharmacokinetics mainly in the dose levels studied, with toxicokinetics focusing on higher toxic doses. The kinetics at these levels can be non-linear due to altered physiological processes. Toxicodynamics examines the relationship...
