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Electrical cardioversion after amiodarone administration.

J Sagristà-Sauleda1, G Permanyer-Miralda, J Soler-Soler

  • 1Servicio de Cardiologia, Hospital General Universitari Vall d'Hebron, Barcelona, Spain.

American Heart Journal
|June 1, 1992
PubMed
Summary
This summary is machine-generated.

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Electrical cardioversion for supraventricular arrhythmias is safe in patients on amiodarone therapy. This study found that while amiodarone may increase ventricular premature beats, standard precautions ensure safe electrical cardioversion.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • The impact of amiodarone on electrical cardioversion for supraventricular tachyarrhythmias remains unclear.
  • Amiodarone is frequently used for long-term management of arrhythmias.

Purpose of the Study:

  • To evaluate the efficacy and safety of electrical cardioversion in patients undergoing amiodarone therapy.
  • To assess potential complications associated with amiodarone use during cardioversion.

Main Methods:

  • 130 electrical cardioversions were performed on patients on long-term oral amiodarone (Group I).
  • 44 electrical cardioversions were performed on patients receiving intravenous amiodarone infusions (Group II).
  • Both groups had atrial fibrillation or flutter; Group I was compared to a control group of 100 cardioversions.

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Main Results:

  • Group I showed a higher incidence of ventricular premature beats compared to controls.
  • One patient in Group I experienced severe bradycardia with asystole, which resolved.
  • Group II exhibited increased sinus bradycardia and ventricular premature beats.

Conclusions:

  • Electrical cardioversion for supraventricular arrhythmias is safe in patients on long-term oral or intravenous amiodarone.
  • Standard precautions are essential for safe cardioversion in this patient population.
  • Amiodarone may increase the occurrence of certain arrhythmias during cardioversion but does not preclude the procedure.