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Related Experiment Videos

Atrioventricular block during adenosine thallium imaging.

J Lee1, J Heo, J D Ogilby

  • 1Philadelphia Heart Institute, Presbyterian Medical Center of Philadelphia, PA 19104.

American Heart Journal
|June 1, 1992
PubMed
Summary
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Transient atrioventricular (AV) block during adenosine thallium imaging is common and usually well-tolerated. This temporary block typically occurs early in the infusion and resolves without intervention, even in patients with normal thallium scan results.

Area of Science:

  • Cardiology
  • Nuclear Cardiology
  • Pharmacology

Background:

  • Transient atrioventricular (AV) block is a known potential side effect of adenosine administration during myocardial perfusion imaging.
  • Understanding the predictors and clinical significance of this transient AV block is crucial for patient safety and accurate interpretation of imaging results.

Purpose of the Study:

  • To investigate the predictors and hemodynamic implications of transient second- or third-degree atrioventricular (AV) block during adenosine thallium imaging.
  • To compare the characteristics and outcomes of patients experiencing AV block with those who did not.

Main Methods:

  • Retrospective analysis of 858 patients undergoing adenosine thallium imaging.
  • Comparison of 55 patients with second- or third-degree AV block (group 1) against 803 patients without AV block (group 2).

Related Experiment Videos

  • Evaluation of baseline characteristics, clinical symptoms, medication use, and thallium imaging results.

    • Main Results:

    • No significant differences in age, sex, baseline heart rate, pre-existing conduction abnormalities, or use of digitalis and beta-blockers between groups.
    • AV block occurred within the first two minutes of adenosine infusion in 73% of affected patients and resolved despite continued infusion in 78%.
    • Hemodynamic parameters during AV block (heart rate 79±18 bpm, systolic blood pressure 127±27 mm Hg) were generally stable, with premature termination required in only 2%.

    Conclusions:

    • Transient AV block during adenosine thallium imaging is common, typically occurs early, and is often well-tolerated with no significant hemodynamic compromise.
    • The occurrence of AV block is not associated with specific patient demographics, baseline conduction abnormalities, or common cardiac medications like digitalis or beta-blockers.
    • Adenosine-induced AV block can occur even in patients with normal myocardial perfusion imaging results and does not necessitate routine aminophylline administration.