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Leprosy in Britain: 50 years experience in Liverpool.
QJM : Monthly Journal of the Association of Physicians
|June 16, 2005
Summary
Leprosy, a chronic infection causing skin and nerve issues, requires careful consideration in travelers to tropical regions. This review highlights its varied presentation and long-term impacts.
Area of Science:
- Tropical Medicine
- Infectious Diseases
- Dermatology
Background:
- Leprosy is a chronic infection with diverse dermal and neurological symptoms.
- It can lead to significant disability, morbidity, and social stigma.
Purpose of the Study:
- To review leprosy patients at the Liverpool School of Tropical Medicine (LSTM) from 1946-2003.
- To analyze country of birth/infection, clinical presentation, diagnosis, management, and reactions.
Main Methods:
- Retrospective review of 50 patient clinical records from 1946-2003.
- Inclusion of letters, casenotes, radiographs, and photographs.
- Recording of co-existing tuberculosis or diabetes history.
Main Results:
- Most patients (64%) were from the Indian subcontinent, with 62% contracting leprosy there.
- Common presentations: anesthetic skin lesions (36%), hypopigmentation (30%), nerve enlargement (50%).
- Diagnosis combined clinical data and biopsy (60%); slit skin smears positive in 61% of multibacillary cases. Reactions occurred in 42% of patients.
Conclusions:
- Leprosy is a crucial diagnosis for those with tropical travel/work history.
- The condition has profound medical, social, and emotional consequences.
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