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The fasciitis-morphea complex in children.
1Lucille Salter Packard Children's Hospital, Stanford, Palo Alto, CA 94304.
American Journal of Diseases of Children (1960)
|June 1, 1992
Summary
Fasciitis and morphea are linked childhood conditions. Steroids help fasciitis, while penicillamine may improve morphea sclerosis but not new lesions.
Area of Science:
- Pediatric Rheumatology
- Dermatology
- Pediatric Autoimmune Diseases
Background:
- This study investigates the combined syndrome of fasciitis and morphea in children.
- Understanding this rare co-occurrence is crucial for accurate diagnosis and management.
Observation:
- Six children with fasciitis symptoms were evaluated.
- Morphea symptoms manifested from 1 year prior to 4 years after fasciitis onset.
- Fasciitis presented with symmetrical swelling, pain, and contractures; morphea and fasciitis affected different body areas.
Findings:
- Fasciitis and morphea are interconnected clinical manifestations in pediatric patients.
- Corticosteroid therapy demonstrated efficacy in treating the fasciitis component.
- Penicillamine showed potential in ameliorating morphea-related sclerosis, though it did not prevent new lesion development.
Implications:
- Early recognition of this combined syndrome is vital for effective treatment strategies.
- Tailored therapeutic approaches are necessary, considering the differential response of fasciitis and morphea to treatments.
- Further research is warranted to explore the underlying mechanisms and optimize management for children with coexisting fasciitis and morphea.