Related Experiment Video

Updated: Jan 30, 2026

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.3K

Prevalence of Helicobacter pullorum among patients with gastrointestinal disease and clinically healthy persons

Liesbeth Ceelen1, Annemie Decostere, Gerda Verschraegen

  • 1Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. liesbeth.ceelen@UGent.be

Journal of Clinical Microbiology
|June 16, 2005
PubMed

Insights

Helicobacter pullorum was detected in the feces of both patients with gastroenteritis and healthy individuals using PCR. This suggests H. pullorum may not be a primary cause of gastrointestinal disease.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Gastroenterology

Background:

  • Helicobacter pullorum is a bacterium that can cause gastrointestinal issues.
  • Its role in causing gastroenteritis in humans is not fully understood.

Purpose of the Study:

  • To investigate the prevalence of Helicobacter pullorum in patients with gastroenteritis.
  • To determine if H. pullorum is associated with gastrointestinal disease.

Main Methods:

  • Fecal samples from 531 gastroenteritis patients and 100 healthy controls were analyzed.
  • Polymerase Chain Reaction (PCR) was used to detect H. pullorum DNA.
  • Positive samples were cultured for bacterial isolation.

Main Results:

  • H. pullorum DNA was found in 4.3% of gastroenteritis patients.
  • H. pullorum DNA was also detected in 4.0% of healthy individuals.
  • One H. pullorum strain was successfully isolated from a patient with gastrointestinal disease.

Conclusions:

  • Helicobacter pullorum DNA is present in both symptomatic and asymptomatic individuals.
  • The findings suggest H. pullorum may not be a significant causative agent of gastroenteritis.
  • Further research is needed to clarify the pathogenic potential of H. pullorum.

More Related Videos

Mouse Models Of Helicobacter Infection And Gastric Pathologies07:43

Mouse Models Of Helicobacter Infection And Gastric Pathologies

Published on: October 18, 2018

22.5K
Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients13:50

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Published on: June 11, 2011

12.7K

Related Concept Videos

Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
154
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
641
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
368
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.8K
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
933
Anatomy of the Gastrointestinal System01:26

Anatomy of the Gastrointestinal System

The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs.
Here's a detailed walkthrough of this complex system:
2.8K