Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple attack study on the available triptans in Italy versus placebo.

C Vollono1, A Capuano, D Mei

  • 1Headache Center, Università Cattolica del Sacro Cuore, Rome, Italy.

European Journal of Neurology
|June 17, 2005
PubMed
Summary

This study compared five triptans for migraine relief. All tested triptans showed similar efficacy and good tolerability, suggesting personalized triptan selection may be beneficial.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The Beiping Pharmacy Evening School: the pioneer pharmaceutical vocational training in the period of the Republic of China].

Zhonghua yi shi za zhi (Beijing, China : 1980)·2026
Same author

Clinical relevance and methodological approach for the assessment of drug-drug interactions in cancer patients: a position statement from the Italian Association of Medical Oncology (AIOM) and the Italian Society of Pharmacology (SIF).

ESMO open·2025
Same author

Hypogammaglobulinemia and severe infections in Multiple Sclerosis patients on anti-CD20 agents: A multicentre study.

Multiple sclerosis and related disorders·2024
Same author

Comparative effectiveness and cost-effectiveness of natalizumab and fingolimod in rapidly evolving severe relapsing-remitting multiple sclerosis in the United Kingdom.

Journal of medical economics·2023
Same author

Role of active and environmental tobacco smoke on susceptibility to osteoporosis in women undergoing dual-X-ray absorptiometry.

Journal of endocrinological investigation·2023
Same author

Responsiveness to warning sensations and anxiety-related psychological traits modulate individual differences in preference for vegetable foods with varied sensory properties.

Food research international (Ottawa, Ont.)·2023

Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Migraine is a common neurological disorder.
  • Triptans are a class of drugs used to treat migraine attacks.

Purpose of the Study:

  • To evaluate the efficacy and tolerability of five commercially available triptans in Italy.
  • To compare zolmitriptan, rizatriptan, sumatriptan, almotriptan, and eletriptan.
  • To assess treatment outcomes including pain relief and sustained pain freedom.

Main Methods:

  • Single-blind, placebo-controlled study over 18 months.
  • 42 patients with episodic migraine (with or without aura) participated.
  • Each patient used a different triptan for five consecutive migraine crises.

Main Results:

Related Experiment Videos

  • No significant differences in efficacy were observed among the five triptans.
  • All triptans demonstrated good tolerability.
  • Intra-patient consistency and sustained pain relief were evaluated.

Conclusions:

  • The studied triptans are similarly effective and well-tolerated for migraine treatment.
  • Individualized triptan therapy may help identify the optimal drug for each patient.
  • Further research could explore personalized treatment strategies for migraineurs.