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Published on: September 20, 2020
[Necessity of prophylactic antibiotics in patients with primary liver cancer undergoing transcatheter arterial
Jiang-yun Wang1, Yong Chen, Wei Lu
1Department of Interventional Therapy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Objective:
To investigate the necessity of prophylactic administration of antibiotic in patients with primary liver cancer undergoing transcatheter arterial chemoembolization (TACE).
Methods:
Sixty patients without preoperative infection were randomized into two groups to receive a single dose of cefazolin (PA group) prior to TACE or no prophylactic antibiotics (NONE group). The incidence of postoperative infection was compared.
Results:
The incidence of postoperative infection was 3.4% (1/29) in NONE group and 3.2% (1/31) in PA group, without significant difference between the two groups (P>0.05).
Conclusion:
Prophylactic antibiotics are not necessary for patients with primary liver cancer prior to TACE.
