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Edema and malignancy in meningiomas.
Tobias Alécio Mattei1, Josias Alécio Mattei, Ricardo Ramina
1Department of Neurosurgery, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil. tobiasmattei@hotmail.com
Clinics (Sao Paulo, Brazil)
|June 18, 2005
Summary
The degree of peritumoral edema, assessed using computer tomography and magnetic resonance imaging, significantly correlates with meningioma
Area of Science:
- Neurosurgery
- Oncology
- Radiology
Background:
- Meningiomas are tumors arising from the meninges.
- Classifying aggressive meningiomas often involves histopathology and imaging.
- Peritumoral edema is a common finding in meningiomas.
Purpose of the Study:
- To evaluate peritumoral edema using computer tomography (CT) and magnetic resonance imaging (MRI).
- To correlate edema levels with the World Health Organization (WHO) histological classification of meningiomas.
- To review reported causes and relationships of tumoral edema to histological characteristics.
Main Methods:
- Reviewed cases of 55 meningioma patients who underwent surgery.
- Assessed edema level using the classification by Ide et al. (1995).
- Compared edema levels with the WHO histological classification.
Main Results:
- Edema levels observed: Level 0 (28 cases), Level I (19 cases), Level II (8 cases).
- Histological classification: Benign (43 cases), Atypical (11 cases), Malignant (1 case).
- Significant correlation (P=.0089) found between edema degree and histological characteristics.
Conclusions:
- Degree of edema, visualized by CT and MRI, is a significant clinical predictor.
- Edema assessment can aid in predicting the histological grade of meningiomas.
- Imaging-based edema evaluation offers valuable prognostic information.