Related Experiment Video
Updated: Aug 17, 2026

Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis
Published on: June 10, 2022
[28-year-old woman with Goodpasture's syndrome and nonspecific colitis]
Lucyna Jóźwiak1, Grazyna Orłowska-Kowalik, Andrzej Ksiazek
1Katedra i Klinika Nefrologii AM, Lublinie.
Abstract:
Goodpasture's syndrome usually becomes manifest with progressive glomerulonephritis and pulmonary hemorrhage. The diagnostic hallmark is the demonstration of anti-basement membrane anti-alpha3 type IV collagen antibodies (anti-GMB antibodies) in patient sera. Herein is reported the case of 28-year-old woman with Goodpasture's syndrome who developed the acute symptoms of nonspecific colitis which required surgical intervention. Immunosuppression along with plasmapheresis was successful in the treatment of life-threatening pulmonary hemorrhage, but not for the improvement of renal function.
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