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Updated: Aug 17, 2026

T Cells Capture Bacteria by Transinfection from Dendritic Cells
Published on: January 13, 2016
Infection, autoimmunity, and glycolipids: T cells detect microbes through self-recognition
Mitchell Kronenberg1, Yuki Kinjo
1La Jolla Institute for Allergy and Immunology, San Diego, California 92121, USA.
Abstract:
De Libero et al. (2005) demonstrate in this issue of Immunity that bacterial infection leads to increased synthesis of autologous glycolipids that are recognized by CD1-restricted human T cells, indicating that recognition of inducible self-glycolipids could be a mechanism for microbial detection. This mechanism also may provide a connection between infection and autoimmunity.
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