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Published on: August 16, 2018
Biosynthesis of pyrethrin I in seedlings of Chrysanthemum cinerariaefolium
Kazuhiko Matsuda1, Yukio Kikuta, Atsushi Haba
1Department of Applied Biological Chemistry, School of Agriculture, Kinki University, 3327-204 Nakamachi, Nara 631-8505, Japan. kmatsuda@nara.kindai.ac.jp
Abstract:
The biosynthetic pathway to natural pyrethrins in Chrysanthemum cinerariaefolium seedlings was studied using [1-13C]d-glucose as a precursor, with pyrethrin I isolated using HPLC from a leaf extract. The 13C NMR spectrum of pyrethrin I from the precursor-administered seedlings indicated that the acid moiety was biosynthesized from d-glucose via 2-C-methyl-d-erythritol 4-phosphate, whereas the alcohol moiety was possibly biosynthesized from linolenic acid.
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