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Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
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Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled

Mark J Osborn1, Angela Panoskaltsis-Mortari, Ron T McElmurry

  • 1Pediatrics, Hematology-Oncology, Blood and Marrow Transplant Program, Institute of Human Genetics, Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|June 21, 2005
PubMed

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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...