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Medicinal plants and antimicrobial activity.

J L Ríos1, M C Recio

  • 1Departament de Farmacología, Facultat de Farmàcia, Universitat de València. Av. Vicent Andrés Estellés s/n. 46100 Burjassot, Valencia, Spain. riosjl@uv.es

Journal of Ethnopharmacology
|June 21, 2005
PubMed
Summary

Medicinal plants are a vital source of antimicrobial compounds. Research into their anti-infection potential has significantly increased, highlighting the need for standardized study methods.

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Area of Science:

  • Ethnobotany and Phytochemistry
  • Pharmacology and Microbiology

Background:

  • Ethnopharmacological research has increasingly focused on medicinal plants for novel anti-infection agents.
  • The number of publications on the antimicrobial activity of medicinal plants has more than doubled between 1995-2004 compared to 1966-1994.

Purpose of the Study:

  • To analyze the historical, current, and future role of medicinal plants as antimicrobial crude drugs and sources of natural anti-infection compounds.
  • To review the methodologies and scope of studies investigating the antimicrobial activity of medicinal plants.

Main Methods:

  • Literature review of articles on antimicrobial activity of medicinal plants published in PubMed.
  • Analysis of study criteria, including plant extracts, essential oils, isolated compounds (alkaloids, flavonoids, etc.), regional flora, and specific plant-microorganism interactions.

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Main Results:

  • A substantial increase in research articles on the antimicrobial activity of medicinal plants was observed over decades.
  • Studies investigate diverse aspects, from crude plant extracts and essential oils to isolated bioactive compounds and their efficacy against specific pathogens.

Conclusions:

  • Medicinal plants represent a significant reservoir for discovering new antimicrobial agents.
  • Standardization of parameters like plant material, techniques, growth media, and tested microorganisms is crucial for reliable antimicrobial activity studies.