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Intussusception and rotavirus associated hospitalisation in New Zealand

Y E Chen1, S Beasley, K Grimwood

  • 1Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.

Archives of Disease in Childhood
|June 21, 2005
PubMed

Insights

Intussusception in New Zealand affects infants primarily in their first year, with lower risk in females and Maori. Wild-type rotavirus does not appear to trigger this condition.

Area of Science:

  • Pediatric Epidemiology
  • Infectious Disease Epidemiology

Background:

  • Intussusception is a significant cause of intestinal obstruction in infants.
  • Understanding its epidemiology is crucial for public health initiatives, including vaccination programs.

Purpose of the Study:

  • To determine the epidemiology of intussusception in New Zealand children under three.
  • To investigate the relationship between intussusception and rotavirus hospitalizations.

Main Methods:

  • Reviewed national hospital discharge data (1998-2003) for intussusception cases in children <3 years.
  • Prospectively identified children with rotavirus gastroenteritis in eight pediatric units (1998-2000).
  • Compared epidemiological characteristics of intussusception cases with rotavirus cases.

Main Results:

  • 277 intussusception cases were identified with no deaths over 5.5 years.
  • 72% of cases occurred in the first year of life; incidence rate was 65 per 100,000 child-years.
  • Lower risk observed in females and Maori infants compared to European infants; intussusception peaked younger and lacked seasonality compared to rotavirus cases.

Conclusions:

  • Established national baseline data for intussusception in New Zealand, informing future rotavirus vaccine programs.
  • Wild-type rotaviruses do not seem to be a primary trigger for intussusception.
  • Recommended prospective surveillance with standardized definitions for better understanding of intussusception etiology and epidemiology.
Abstract

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