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Updated: Aug 17, 2026

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

Using DNA shuffling to create novel infectious bronchitis virus S1 genes: implications for S1 gene recombination

Scott Callison1, Deborah Hilt, Mark Jackwood

  • 1Department of Avian Medicine, Poultry Diagnostic and Research Center, The University of Georgia, Athens, GA 30605, USA.

Virus Genes
|June 21, 2005
PubMed

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The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
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