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Published on: July 17, 2021
Characterisation of variant alleles in the STR systems D2S1338, D3S1358 and D19S433
Marielle Heinrich1, Heike Felske-Zech, Bernd Brinkmann
1Institut für Rechtsmedizin, Universitätsklinikum Münster, Röntgenstr. 23, 48149 Münster, Germany.
Abstract:
We have observed three hitherto undescribed off-ladder alleles at three widely used STR loci. These were isolated, sequenced and designated as follows: allele 10 (D2S1338, one case), allele 21 (D3S1358, two cases) and allele 6.2 (D19S433, six cases). These sequences are described in comparison to non-variant alleles, and their implications for the semi-automated STR analysis will be discussed.
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