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Metabolic Pathway Confirmation and Discovery Through 13C-labeling of Proteinogenic Amino Acids
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Biosynthesis of C14-labeled amino acids by Chlorella ellipsoidae

T Wada1, M Nomura, H Mitsui

  • 1Division of Enzymology, The Institute of Applied Microbiology, University of Tokyo, Tokyo, Japan.

The Journal of General and Applied Microbiology
|June 21, 2005
PubMed
Abstract

No abstract available in PubMed .

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Amino acid biosynthesis is essential for cell growth, protein synthesis, and metabolic regulation. Cells generate essential and non-essential amino acids from metabolic intermediates to sustain vital biological functions. These intermediates originate from key metabolic pathways: glycolysis, the tricarboxylic acid (TCA) cycle, and the pentose phosphate pathway. Important precursors include α-ketoglutarate, pyruvate, oxaloacetate, phosphoenolpyruvate, and erythrose-4-phosphate, which provide...

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