Related Experiment Video
Updated: Aug 17, 2026

Phage-Mediated Genetic Manipulation of the Lyme Disease Spirochete Borrelia burgdorferi
Published on: September 28, 2022
DNA base composition, susceptibility to bacteriophages and interspecific transformation as criteria for
Yonosuke Ikeda1, Hiuga Saito, Kin-ichiro Miura
1Institute of Applied Microbiology, University of Tokyo, Tokyo.
Abstract:
With 25 strains belonging to 12 species of the genus Bacillus, the base composition of DNA, the susceptibility to bacteriophages, and the ability to transform Bacillus subtilis strain Marburg were studied. Analyses of phage DNAs were also performed. The results were as follows: (1) The DNA base compositions were not uniform even among strains belonging to one taxonomic species. (2) The DNAs extracted from B. natto, B. megaterium and B. polymyxa could transform genetic traits of B. subtilis Marburg although the frequencies were not equal. (3) The host ranges of some temperate bacteriophages were correlated with the taxonomical data. On these bases, the phylogenetic relatedness of B. subtilis to B. megaterium was discussed.
Related Concept Videos
Bacterial Transformation
Bacterial Transformation
DNA Bacteriophages
Transformation
Transduction
Genomic DNA in Prokaryotes
Genomic Diversity in Bacteria
Although bacterial genomes are much...

