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Published on: January 20, 2023
Clinical and echocardiographic aspects of mid-ventricular hypertrophic cardiomyopathy
Francisco Martínez Baca-López1, Ana Lilia Rayas-Gómez, Erick Ramírez-Arias
1Department of Echocardiography, Hospital of Cardiology XXI Century National Medical Center, IMSS, Mexico City, Mexico. drerickrmzarias@hotmail.com
Insights
Hypertrophic cardiomyopathy with apical aneurysm and mid-ventricular obstruction presents unique diagnostic challenges. Echocardiography and cardiac catheterization are crucial for identifying characteristic findings like mid-ventricular obliteration and intraventricular gradients.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Hypertrophic cardiomyopathy (HCM) can manifest with complex anatomical variations.
- Mid-ventricular obstruction presents a diagnostic challenge, often requiring advanced imaging techniques.
Observation:
- Three cases of HCM with apical aneurysm and mid-ventricular obstruction are presented.
- Two patients were diagnosed using two-dimensional and Doppler echocardiography, revealing mid-ventricular obliteration, an hourglass image, and paradoxic jet flow.
- One patient required contrast echocardiography due to suboptimal initial imaging.
Findings:
- Clinical presentation included angina and dyspnea.
- Thallium myocardial imaging showed apical perfusion abnormalities, suggesting ischemia or necrosis.
- Cardiac catheterization confirmed mid-ventricular obliteration, significant intraventricular gradients, and normal coronary arteries.
Implications:
- Early and accurate diagnosis of this HCM variant is essential for appropriate management.
- Multimodality imaging plays a critical role in characterizing complex left ventricular outflow tract obstructions.
- Understanding these specific HCM phenotypes aids in predicting clinical outcomes and guiding therapeutic strategies.
Abstract:
Three cases of patients with hypertropic cardiomyopathy, apical aneurysm, and mid-ventricular obstruction are presented. Two patients were diagnosed first by two-dimensional and Doppler echocardiography, which showed mid-ventricular obliteration, characteristic hourglass image, and paradoxic jet flow. One patient with suboptimal echocardiogram was necessary to perform contrast echocardiogram. Clinical picture was characterized by angina and dyspnea. Thallium myocardial imaging revealed perfusion abnormalities in apical region, ischemia or necrosis. Cardiac catheterism showed mid-ventricular obliteration and significant intraventricular gradient and coronary arteries angiography without lesions.
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