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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
Published on: August 31, 2014
Molecular cloning of monkey histamine H4 receptor
Tamaki Oda1, Shun-ichiro Matsumoto, Mitsuyuki Matsumoto
1Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd., Ibaraki, Japan.
Abstract:
Histamine H(4) receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H(4) receptor was identified. Monkey H(4) receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H(4) receptor will contribute to a better interpretation of effective drug discovery.
