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Related Experiment Videos

Ergotamine-induced upper extremity ischemia: a case report.

Man Deuk Kim1, Gun Lee, Sung Wook Shin

  • 1Department of Diagnostic Radiology, Bundang CHA General Hospital, Pochon CHA University, Kyonggi-do, Korea. mdkim@cha.ac.kr

Korean Journal of Radiology
|June 22, 2005
PubMed
Summary
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Ergotamine, used for migraines, can cause rare limb ischemia. A man developed right arm ischemia from long-term Ergot use, successfully treated with nitroprusside.

Area of Science:

  • Vascular Medicine
  • Neurology

Background:

  • Ergotamine is a medication primarily used for treating migraine headaches.
  • Long-term use of ergotamine carries potential risks, including vascular complications.

Observation:

  • A 64-year-old male patient presented with ischemia in his right upper extremity.
  • The patient had a history of long-term ergotamine use for managing migraine headaches.

Findings:

  • Angiography demonstrated diffused, smooth, and tapered narrowing of the brachial artery.
  • This vascular narrowing was attributed to ergotamine-induced vasospasm.

Implications:

  • This case highlights an extremely rare but serious adverse effect of ergotamine.
  • Intravenous nitroprusside proved effective in treating ergotamine-induced limb ischemia.

Related Experiment Videos

  • Clinicians should consider ergotamine toxicity in patients with unexplained limb ischemia, especially with a history of its use.