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Psoriasis--recent advances in understanding its pathogenesis and treatment

Gerald Krueger1, Charles N Ellis

  • 1Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA. krueger@derm.med.utah.edu

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EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
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Pharmacogenomics: Identification of New Drug Targets

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