Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

In-plane velocity encoding with coherent steady-state imaging.

John Grinstead1, Shantanu Sinha

  • 1Department of Radiological Sciences, University of California-Los Angeles, Los Angeles, California 90024, USA.

Magnetic Resonance in Medicine
|June 22, 2005
PubMed
Summary

This study introduces a novel method for phase-contrast flow quantification (PC-FQ) using unspoiled SS coherent (SSC) sequences, enhancing signal-to-noise ratio (SNR). The improved technique promises more precise blood flow measurements in medical imaging.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between posterior cerebral artery involvement and arterial wall enhancement in moyamoya disease: a cross-sectional study with vessel wall imaging.

Neuroradiology·2026
Same author

Investigating the correlation between force output, strains, and pressure for active skeletal muscle contractions.

Journal of the mechanical behavior of biomedical materials·2026
Same author

Association between ischemic stroke and hyperintense plaques detected by high-resolution vessel wall MRI in Japanese patients with intracranial atherosclerotic disease.

Frontiers in stroke·2026
Same author

Whole-Plaque Adventitial Enhancement on Contrast-Enhanced MRI DANTE T1-SPACE as a Marker of Carotid Plaque Vulnerability.

World neurosurgery·2025
Same author

Evaluation of meningeal lymphatic vessels with delayed contrast enhanced vessel-wall MRI in cerebral infarction.

Japanese journal of radiology·2025
Same author

Evaluation of Magnetization Transfer Contrast Sequences: Application to Monitor Age-Related Differences in Muscle Macromolecular Fraction.

Tomography (Ann Arbor, Mich.)·2025

Area of Science:

  • Medical Imaging
  • Biophysics
  • Cardiovascular Research

Background:

  • Standard phase-contrast flow quantification (PC-FQ) using radiofrequency (RF) spoiled steady-state (SS) sequences suffer from low signal-to-noise ratio (SNR).
  • Unspoiled SS coherent (SSC) sequences offer higher intrinsic SNR and T2/T1 weighting, providing better blood signal contrast.
  • Existing velocity encoding methods can increase repetition time (TR) and sensitivity to off-resonance artifacts in SSC sequences.

Purpose of the Study:

  • To present a modified SSC gradient-echo sequence for in-plane velocity encoding.
  • To evaluate the performance of the new velocity encoding technique compared to standard PC-FQ.
  • To assess the potential of the method for increasing the precision of PC-FQ measurements.

Main Methods:

Related Experiment Videos

  • Modified an unspoiled SS coherent (SSC) gradient-echo sequence to incorporate in-plane velocity encoding by inverting readout gradients.
  • Avoided increasing repetition time (TR) to mitigate off-resonance artifacts.
  • Conducted in vitro experiments with constant and sinusoidal flow, and in vivo imaging of the carotid artery.

    • Main Results:

    • The modified SSC sequence achieved in-plane velocity encoding without increasing TR.
    • Comparison with standard PC-FQ showed comparable and potentially improved velocity data visualization.
    • Vector field maps and particle-tracking calculations demonstrated the utility of the new method.

    Conclusions:

    • The novel SSC sequence with inverted readout gradients enables precise in-plane velocity encoding.
    • This technique enhances SNR and avoids common artifacts associated with conventional methods.
    • The method holds significant potential for improving the accuracy and precision of phase-contrast flow quantification in clinical applications.