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Updated: Aug 17, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
Published on: April 29, 2007
[Diagnosis and therapy of Parkinson's disease]
1Klinik und Poliklinik für Neurologie, Universität Rostock. matthias.wittstock@med.uni-rostock.de
Abstract:
The clinical diagnosis of Parkinson's disease is mainly based upon the principal symptoms bradykinesia, rigidity and tremor at rest. The differential diagnosis of idiopathic Parkinson's disease (IPD) from other parkinsonisms is from the prognostic and therapeutic standpoint of considerable importance because the Parkinson-Plus syndrome generally does not or only poorly responds to a dopaminergic therapy. The treatment of IPD comprises, in addition to, dopaminergic medications such as L-dopa or dopamine receptor agonists, operative therapeutic options such as deep brain stimulation and nondrug therapies.
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