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A child with transient neurologic deficits and headache associated with cerebrospinal fluid pleocytosis

Robert Safier1, Gulay Alper

  • 1Division of Child Neurology, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA.

Journal of Child Neurology
|June 23, 2005
PubMed

Insights

A pediatric case presented with recurrent neurological symptoms and cerebrospinal fluid abnormalities. The condition resolved spontaneously, indicating a benign, monophasic illness with an unknown cause.

Area of Science:

  • Pediatric Neurology
  • Neuroimmunology
  • Infectious Diseases

Background:

  • Recurrent neurological symptoms in children can be challenging to diagnose.
  • Cerebrospinal fluid (CSF) analysis is crucial for evaluating central nervous system disorders.
  • Differentiating benign conditions from serious pathologies is essential for appropriate management.

Observation:

  • A 10-year-old girl experienced recurrent episodes of severe headache, altered consciousness, and transient neurological deficits over two months.
  • Cerebrospinal fluid examination revealed lymphocytic pleocytosis and elevated protein levels.
  • Comprehensive microbiological workup and neuroimaging studies yielded negative results.

Findings:

  • CSF parameters normalized within three months.
  • The patient remained symptom-free for 15 months post-initial evaluation.
  • The clinical presentation suggests a benign, self-limiting neurological condition.

Implications:

  • This case highlights a rare, benign neurological syndrome in a pediatric patient.
  • The etiology remains undetermined, warranting further research into potential triggers or mechanisms.
  • Such cases underscore the importance of thorough investigation and long-term follow-up in pediatric neurology.

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