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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
Characteristics of intermittent and persistent allergic rhinitis: DREAMS study group
J Bousquet1, I Annesi-Maesano, F Carat
1University Hospital and INSERM U454, Montpellier, France. jean.bousquet@wanadoo.fr
Summary
The Allergic Rhinitis and its Impact on Asthma (ARIA) classification redefines rhinitis types. Persistent rhinitis, especially severe forms, is linked to higher asthma prevalence, underscoring the need for asthma evaluation in these patients.
Area of Science:
- Allergy and Clinical Immunology
- Respiratory Medicine
Background:
- The Allergic Rhinitis and its Impact on Asthma (ARIA) classification proposed intermittent and persistent rhinitis to replace seasonal and perennial allergic rhinitis (AR).
- Understanding the nuances of this new classification is crucial for accurate diagnosis and management of AR.
Purpose of the Study:
- To investigate the characteristics of patients classified under the ARIA rhinitis categories.
- To examine allergen sensitization and co-morbidities, particularly asthma, in relation to ARIA rhinitis classifications.
Main Methods:
- A cross-sectional study involving 591 AR patients and 502 controls was conducted.
- Patients were diagnosed using the SFAR score and categorized into four ARIA classes.
- Allergen sensitization (SPT, specific IgE) and co-morbidities were assessed per ARIA class.
Main Results:
- The majority of patients (59%) presented with moderate/severe persistent rhinitis.
- A significant association was found between rhinitis and asthma (24% vs 2% in controls, P<0.0001).
- Moderate/severe persistent rhinitis showed the highest asthma prevalence (33%).
Conclusions:
- Intermittent and persistent rhinitis classifications are not direct equivalents to seasonal and perennial types.
- Most specialist-consulting patients exhibit severe rhinitis.
- Increased asthma prevalence with rhinitis severity supports ARIA's recommendation for asthma evaluation in persistent rhinitis cases.
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