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Updated: Aug 6, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
[Monoclonal gammopathy: a frequently overlooked diagnosis]
M Batuecas Mohedano1, J A Piqueras Argüello, F Carballo Alvarez
1Laboratorio de Análisis Clínicos, Hospital Universitario de Guadalajara, SESCAM. miriambatuecas@hotmail.com
Objective:
To know the rate of occurrence of monoclonal bands in a clinical laboratory as an estimate of monoclonal gammopathy incidence, and to detect the proportion of these bands in which an explicit clinical diagnosis or follow-up request is not established. Other objectives are to describe its distribution and the characteristics of the patients.
Patients And Methods:
200 patients were studied in which a monoclonal band had been detected de novo.
Results:
The incidence was 6.59 x 10(-4) year(-1). In 59.5% a diagnostic assumption was not stated. Most frequent diagnosis in the group of patients with a diagnosis was monoclonal gammopathy with uncertain meaning. Average age of patients was 74.4 years and the difference between percentages by sex was statistically significant.
Discussion:
The data suggest a lack of clinical effort when the result is the appearance of a monoclonal band. There is no discrepancy in the distribution of the bands and in the characteristics of the patients with regard to what is described in other studies.
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