Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Antimalarials in systemic diseases].

P Tutor-Ureta1, M Yebra-Bango

  • 1Servicio de Medicina Interna, Hospital Universitario Puerta de Hierro, Madrid.

Revista Clinica Espanola
|June 23, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Short-term atorvastatin therapy improves arterial stiffness of middle-aged systemic lupus erythematosus patients with pathological pulse wave velocity.

Lupus·2016
Same author

Metabolic syndrome is associated with decreased circulating endothelial progenitor cells and increased arterial stiffness in systemic lupus erythematosus.

Lupus·2015
Same author

Biclonal gammopathies: Retrospective study of 47 patients.

Revista clinica espanola·2014
Same author

Authors' reply.

Scandinavian journal of rheumatology·2014
Same author

[Refractory chronic erythema nodosum treated with adalimumab].

Revista clinica espanola·2013
Same author

Increased arterial stiffness is independently associated with metabolic syndrome and damage index in systemic lupus erythematosus patients.

Scandinavian journal of rheumatology·2013
Same journal

Vaccination status of patients undergoing HIV treatment in a hospital in Madrid.

Revista clinica espanola·2026
Same journal

Sulfonylureas and fracture risk in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.

Revista clinica espanola·2026
Same journal

Risk factors for the development of in-hospital complications in pluripathological patients.

Revista clinica espanola·2026
Same journal

Features, treatment and 1-year prognosis of patients with heart failure and chronic kidney disease stages 4 or 5.

Revista clinica espanola·2026
Same journal

Notification of suspected adverse drug reactions by nurses to a hospital pharmacovigilance program. Retrospective descriptive study.

Revista clinica espanola·2026
Same journal

Venous thromboembolic disease associated with hormonal contraceptives. Venous Thromboembolism Group of the Spanish Society of Internal Medicine and the Catalan Society of Contraception.

Revista clinica espanola·2026
See all related articles

Antimalarials, used for centuries, treat autoimmune diseases like rheumatoid arthritis and lupus. These drugs offer benefits for skin and joint issues, with careful consideration for pregnant women due to potential retinal side effects.

Area of Science:

  • Pharmacology
  • Rheumatology
  • Immunology

Context:

  • Antimalarials have a long history of use, with chloroquine and hydroxychloroquine being widely prescribed.
  • Their mechanisms of action in autoimmune conditions are not fully understood.
  • These drugs are frequently employed in managing autoimmune diseases such as rheumatoid arthritis and lupus erythematosus.

Purpose:

  • To review the use of antimalarials in autoimmune diseases.
  • To discuss their efficacy, adverse effects (particularly retinal), and appropriate dosing.
  • To provide guidance on their use in pregnant women.

Summary:

  • Antimalarials demonstrate efficacy in treating cutaneous and articular manifestations of autoimmune diseases.
  • Benefits extend to improving blood glucose, lipid profiles, and platelet aggregation.

Related Experiment Videos

  • The favorable effectiveness-toxicity ratio supports their consideration in managing autoimmune conditions.

    • Impact:

    • Provides a comprehensive overview of antimalarial therapy in autoimmune disorders.
    • Highlights key considerations for clinical practice, including dosing and adverse event monitoring.
    • Offers insights into the management of autoimmune diseases, especially in specific populations like pregnant women.