Intron position conservation across eukaryotic lineages in tubulin genes
Bagavathi S Perumal1, Kishore R Sakharkar, Vincent Tak Kwong Chow
1NCSV, MAE, Nanyang Technological University, 639798, Singapore.
Abstract:
A compilation of intron positions obtained from a large number of eukaryotic genomes across orthologous tubulins is explored for molecular evolution. Comparison of intron positions for 41 alpha, 80 beta, and 30 gamma tubulin genomic sequences indicates that the putative ancestral tubulin gene contained at least 19, 33, and 52 intron positions distributed at different sites in the coding regions for alpha, beta, and gamma tubulins, respectively. Many intron positions are old and are conserved across different eukaryotic lineages and intron distribution patterns are consistent with 'introns-early' hypothesis.
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