Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Acute cerebral circulation problems].

P D Schellinger1, R Kollmar, U K Meyding-Lamadé

  • 1Neurologische Klinik, Universitätsklinikum Heidelberg. Peter_Schellinger@med.uni-heidelberg.de

Der Internist
|June 23, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Artificial Intelligence Algorithm Integrated into the Clinical Workflow Can Ensure High Quality Acute Intracranial Hemorrhage CT Diagnostic.

Clinical neuroradiology·2024
Same author

Myocardial injury in patients with acute ischemic stroke detected by cardiovascular magnetic resonance imaging.

European journal of radiology·2023
Same author

Key design elements of successful acute ischemic stroke treatment trials.

Neurological research and practice·2023
Same author

Polypharmacy, functional outcome and treatment effect of intravenous alteplase for acute ischaemic stroke.

European journal of neurology·2020
Same author

Pulse pressure variability is associated with unfavorable outcomes in acute ischaemic stroke patients treated with intravenous thrombolysis.

European journal of neurology·2020
Same author

Intravenous thrombolysis for large vessel or distal occlusions presenting with mild stroke severity.

European journal of neurology·2020
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
See all related articles

Acute stroke, a leading cause of death and disability, requires rapid intervention. Current treatments focus on restoring blood flow to the brain

Area of Science:

  • Neurology
  • Emergency Medicine
  • Vascular Medicine

Context:

  • Acute stroke is a major cause of death and permanent disability globally.
  • Ischemic stroke results from cerebral artery occlusion, compromising brain perfusion (penumbra).
  • Treatment strategies target reperfusion and neuroprotection of ischemic penumbral tissue.

Purpose:

  • To outline current diagnostic and treatment paradigms for acute ischemic stroke.
  • To emphasize the time-sensitive nature of stroke interventions.
  • To discuss the role of neuroimaging and reperfusion therapies.

Summary:

  • Diagnosis involves history, neurostatus, and imaging (CT/MRI) to rule out hemorrhage.
  • Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) is effective within 3-4.5 hours.

Related Experiment Videos

  • Advanced therapies like mechanical reperfusion and hemicraniectomy are options for select severe cases, often in specialized centers.

    • Impact:

    • Timely diagnosis and treatment significantly improve patient outcomes.
    • Understanding the penumbra concept guides therapeutic decisions.
    • Ongoing research aims to expand treatment windows and improve reperfusion techniques.