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Related Experiment Videos

Perioral dermatitis: a 12-year review.

D S Wilkinson, V Kirton, J D Wilkinson

    The British Journal of Dermatology
    |September 1, 1979
    PubMed
    Summary

    Perioral dermatitis, a skin condition, dramatically increased until the early 1970s. Prolonged use of potent topical corticosteroids is identified as the primary cause, with tetracyclines proving effective for treatment.

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    Area of Science:

    • Dermatology
    • Cutaneous Medicine
    • Clinical Research

    Background:

    • Perioral dermatitis incidence rose significantly from 1966 to 1972.
    • The study distinguishes perioral dermatitis from similar conditions like circumoral and paranasal dermatitis.

    Purpose of the Study:

    • To investigate the etiological factors of perioral dermatitis.
    • To analyze clinical patterns and treatment outcomes over a 12-year period.

    Main Methods:

    • Retrospective analysis of 203 perioral dermatitis patients diagnosed between 1966 and 1978.
    • Clinical observation and patient history, including topical corticosteroid use.

    Main Results:

    • Prolonged use of potent topical corticosteroids was identified as the primary etiological factor.
    • Tetracycline treatment achieved high cure rates (over 6 weeks) when topical corticosteroids were discontinued.
    • Relapse rates were found to be rare following appropriate treatment.

    Conclusions:

    • Topical corticosteroid misuse is the most probable cause of perioral dermatitis.
    • Perioral dermatitis is a treatable condition with a favorable prognosis.
    • Further research is needed to address remaining questions regarding the condition.

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