Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Integr8 project--a resource for genomic and proteomic data.

Manuela Pruess1, Paul Kersey, Rolf Apweiler

  • 1EMBL Outstation - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.

In Silico Biology
|June 24, 2005
PubMed
Summary

Integr8 offers a unified platform for genomic and proteomic data integration, linking biological entities across major European bioinformatics databases. This system enhances data accessibility and analysis for researchers studying genomes and proteomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Wheat historical phenotypic data from European genebanks as an important resource for research and breeding.

Scientific data·2026
Same author

BrAPI v2: real-world applications for data integration and collaboration in the breeding and genetics community.

Database : the journal of biological databases and curation·2025
Same author

A comparison of 27 Arabidopsis thaliana genomes and the path toward an unbiased characterization of genetic polymorphism.

Nature genetics·2025
Same author

A DNA barcoding framework for taxonomic verification in the Darwin Tree of Life Project.

Wellcome open research·2024
Same author

Data Mining, Quality and Management in the Life Sciences.

Methods in molecular biology (Clifton, N.J.)·2022
Same author

The European Bioinformatics Institute (EMBL-EBI) in 2021.

Nucleic acids research·2021

Area of Science:

  • Bioinformatics
  • Genomics
  • Proteomics

Background:

  • Bioinformatic data is often siloed across multiple databases.
  • Exploiting integrated genomic and proteomic data requires sophisticated tools and frameworks.

Purpose of the Study:

  • To develop an integration layer for genomic and proteomic data exploitation.
  • To store relationships between biological entities and database entries.
  • To provide an entity-centric view of complete genomes and proteomes.

Main Methods:

  • Utilizing databases from major European bioinformatics centers.
  • Implementing an integration layer with tools like Proteome Analysis, International Protein Index (IPI), Universal Protein sequence archive (UniParc), and Genome Reviews.
  • Developing entry points based on user interest (taxonomy, species, protein sequences, genes).

Related Experiment Videos

Main Results:

  • Established relationships between biological entities and cross-database entries.
  • Provided a framework for integrating diverse data types.
  • Offered an entity-centric view of genomes and proteomes.
  • Integrated key bioinformatics databases and tools.

Conclusions:

  • Integr8 provides a comprehensive framework for accessing and analyzing integrated genomic and proteomic data.
  • The system enhances biological data exploitation through unified access and entity-centric views.
  • Researchers can leverage Integr8 for advanced data analysis and discovery.