Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis
Related Experiment Video
Updated: Aug 17, 2026
Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Viswanath P Kurup1, Raghavan Raju, Pachiappan Manickam
1Allergy-Immunolgy Division, Medical College of Wisconsin, and Research Service 151-I, VA Medical Center, 5000 West National Avenue, Milwaukee, Wisconsin 53295, USA. vkurup@mcw.edu
Abstract:
Allergic bronchopulmonary aspergillosis (ABPA) results from the interactions of the Aspergillus allergens and immune system of the patients. We studied the gene expression profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showed enhanced expression and represent chemokine, cytokine, growth factor, signal transduction, and transmembrane receptor genes as well as genes related to arginine metabolism.
