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Retinal pigment epithelium implantation in the rabbit: technique and morphology
A A el Dirini1, H M Wang, T E Ogden
1Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles.
Abstract:
Dysfunction of the retinal pigment epithelium (RPE) is a major component of many degenerative disorders of the retina. We have developed a modified pars plana technique for subretinal implantation of homologous, cultured, carbon-loaded RPE cells in the rabbit. The natural history and morphologic behavior of the implanted RPE cells for up to 6 weeks after transplantation were observed in successful procedures.