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Polymer Microarrays for High Throughput Discovery of Biomaterials
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Ultrahigh density microarrays of solid samples

Matthew J LeBaron1, Heidi R Crismon, Fransiscus E Utama

  • 1Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University Medical Center, NRB E504, 3970 Reservoir Rd. NW, Washington, DC 20057-1469, USA.

Nature Methods
|June 24, 2005
PubMed

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...