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Antibacterial activity of clonidine and neostigmine in vitro

Emmanuel Boselli1, Marion Guillier, Jean Freney

  • 1Service d'Anesthésie-Réanimation, Department of Anesthesiology, Hôpital Edouard Herriot, 5 place d'Arsonval, 69437 Lyon cedex 03, France. emmanuel.boselli@chu-lyon.fr

Anesthesia and Analgesia
|June 25, 2005
PubMed

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Nondepolarizing neuromuscular blockers prevent the membrane depolarization of muscle cells and inhibit muscle contraction. These are usually administered with anesthetics to achieve complete muscle relaxation. Upon administration, these drugs first block the small, rapidly contracting muscles of the face and hands, followed by the larger muscles of the trunk and the intercostal muscles. The diaphragm is the last muscle to be affected.
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