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Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
Published on: July 7, 2016
[Prescriptions in cardiology]
1Académie nationale de médecine, 16, rue Bonaparte, F75272 Paris Cedex 06.
Abstract:
Prescriptions in cardiology have progressed from the often empirical and approximate approach used in the past to more rational approach based on the results of large clinical trials. For high blood pressure, bi- or even tri-therapy is often necessary. For coronary heart disease, betablockers, aspirin, calcium inhibitors, statins and converting enzyme inhibitors constitute the mainstay drugs. For myocardial infarction, the crucial point is to restore muyocardial perfusion as quickly as possible by thrombolysis or angioplasty. Polytherapy is required for heart failure. Finally, for atrial fibrillation, after anticoagulation, sinus rhythm can be restored with anticoagulant cover can be obtained with electrical shock or antiarrhythmic drugs.
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