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Updated: Aug 17, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
Primary and secondary treatment for Helicobacter pylori in the United States
1University of Wisconsin Medical School and Marquette University College of Health Sciences, Milwaukee, Wisconsin, USA.
Abstract:
One of every 4 to 5 patients who receives antimicrobial therapy for Helicobacter pylori will not have successful eradication. Antimicrobial resistance, poor compliance with the antibiotic regimen, and drug-related side effects all play a role in determining the outcome of therapy. This article discusses the issues involved in H. pylori eradication, the mechanism of antibiotic delivery to the mucus layer of the stomach, and primary and secondary treatment strategies for H. pylori in the United States.
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