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A novel bacterium Achromobacter xylosoxidans as a cause of liver abscess: three case reports

Kouichi Asano1, Shuji Tada, Takayuki Matsumoto

  • 1Department of Gastroenterology, Saiseikai Kumamoto Hospital, Chikami 5-3-1, Kumamoto 861-4193, Japan. k-asano@intmed2.med.kyushu-u.ac.jp

Journal of Hepatology
|June 28, 2005
PubMed

Insights

Achromobacter xylosoxidans, a bacterium, can cause opportunistic infections. This study identifies it as an unrecognized cause of liver abscess in humans, particularly in patients with a history of cholecystectomy.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Hepatology

Background:

  • Achromobacter xylosoxidans is an opportunistic pathogen.
  • Liver abscesses are serious intra-abdominal infections.

Observation:

  • A. xylosoxidans was identified in 3 out of 46 patients with liver abscess.
  • Patients presented with a history of cholecystectomy.
  • CT imaging revealed multi-lobulated, 'coral-like' abscesses.
  • Epithelioid granulomas were observed at the abscess periphery.

Findings:

  • Achromobacter xylosoxidans is an unrecognized causative agent of liver abscess.
  • Specific clinicopathologic features are associated with A. xylosoxidans-induced liver abscess.

Implications:

  • Highlights A. xylosoxidans as a potential pathogen in liver abscess cases.
  • Suggests considering A. xylosoxidans in the differential diagnosis of liver abscess.
  • Informs clinical management and diagnostic approaches for liver abscesses.

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