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Patients with severe bowel malabsorption do not have changes in iodine status
Anderson Marilere Navarro1, Vivian Marques Miguel Suen, Isabel Machado Souza
1Division of Clinical Nutrition, Department of Clinical Medicine, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil. andersonnavarro@yahoo.com
Nutrition (Burbank, Los Angeles County, Calif.)
|June 28, 2005
Summary
Patients with short gut syndrome receiving total parenteral nutrition maintain adequate iodine status. Dietary iodine, including iodized salt, is sufficient in Brazil to support iodine levels in these patients.
Area of Science:
- Endocrinology
- Nutritional Science
- Gastroenterology
Background:
- Intestinal malabsorption can lead to nutrient deficiencies.
- Short gut syndrome (SGS) often necessitates total parenteral nutrition (TPN).
- Iodine status is crucial for thyroid function and overall health.
Purpose of the Study:
- To assess iodine status in patients with SGS on TPN.
- To compare iodine status between SGS patients and healthy controls.
- To evaluate the impact of intestinal malabsorption on iodine levels.
Main Methods:
- Studied 27 subjects across three groups: SGS with TPN, healthy controls, and other illnesses with normal digestion.
- Measured iodine intake from food and TPN solutions.
- Assessed urinary iodine excretion and iodine-to-creatinine ratios.
Main Results:
- No statistically significant differences in daily iodine intake or urinary iodine excretion were observed across the groups.
- Iodine intake levels were comparable among patients with SGS on TPN, healthy controls, and those with other illnesses.
- Urinary iodine to creatinine ratios did not differ significantly between the study groups.
Conclusions:
- Dietary iodine, including iodized salt, appears sufficient in Brazil.
- Patients with short gut syndrome on TPN maintain adequate iodine status.
- Intestinal malabsorption did not negatively impact iodine status in this cohort.