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Electrocardiographic findings over time in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Jonathan P Piccini1, Khurram Nasir, Chandra Bomma

  • 1Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

The American Journal of Cardiology
|June 28, 2005
PubMed

Insights

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) often shows electrocardiogram (ECG) changes over time. S-wave prolongation is a key indicator of this disease progression in ARVC patients.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Genetic Heart Diseases

Background:

  • Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is a significant cause of sudden cardiac death.
  • Early identification of disease progression is crucial for risk stratification and management.

Purpose of the Study:

  • To investigate the prevalence and patterns of electrocardiogram (ECG) progression in patients with ARVC.
  • To identify specific ECG markers indicative of ARVC progression.

Main Methods:

  • Serial electrocardiographic (ECG) assessments were performed on 35 patients diagnosed with ARVC.
  • Patients were monitored over a median follow-up period of 43 months.
  • ECG findings were analyzed for evidence of progression over time.

Main Results:

  • A high rate of ECG progression was observed, with 89% of patients showing changes.
  • S-wave prolongation emerged as the most frequent electrocardiogram marker of disease progression.
  • Other ECG abnormalities indicative of ARVC progression were also noted.

Conclusions:

  • Electrocardiogram (ECG) monitoring reveals significant progression in the majority of ARVC patients.
  • S-wave prolongation is a sensitive and prevalent marker for detecting ARVC progression.
  • Serial ECGs are valuable for assessing disease evolution in arrhythmogenic right ventricular dysplasia/cardiomyopathy.

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