Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gingivostomatitis.

Kenneth F Lyon1

  • 1Arizona Veterinary Dentistry and Oral Surgery, 86 West Juniper Avenue, Gilbert, AZ 85233, USA. Lyon2THVet@aol.com

The Veterinary Clinics of North America. Small Animal Practice
|June 28, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Minimotif Miner 4: a million peptide minimotifs and counting.

Nucleic acids research·2017
Same author

The Functional Human C-Terminome.

PloS one·2016
Same author

Natural variability of minimotifs in 1092 people indicates that minimotifs are targets of evolution.

Nucleic acids research·2015
Same author

Evaluation of calciotropic hormones in cats with odontoclastic resorptive lesions.

American journal of veterinary research·2005
Same journal

Regulation of Artificial Intelligence in Veterinary Medicine.

The Veterinary clinics of North America. Small animal practice·2026
Same journal

Practical Steps Toward Antimicrobial Stewardship for the General Practitioner.

The Veterinary clinics of North America. Small animal practice·2026
Same journal

Using Evidence-Based Veterinary Medicine and Artificial Intelligence to Support Clinical Decision Making in Veterinary Practice.

The Veterinary clinics of North America. Small animal practice·2026
Same journal

Feline Asthma-Update on Diagnosis and Treatment Recommendations.

The Veterinary clinics of North America. Small animal practice·2026
Same journal

Disease Prediction and Precision Veterinary Medicine: Applications, Opportunities, and Limitations of Artificial Intelligence in Small Animal Practice.

The Veterinary clinics of North America. Small animal practice·2026
Same journal

The Moving Target of Companion Animal Infectious Diseases: Emerging Threats and Evolving Solutions.

The Veterinary clinics of North America. Small animal practice·2026
See all related articles

Gingivostomatitis treatments vary, but extraction offers a high success rate for severe cases. Combining immunomodulation with cyclosporine and laser therapy is an alternative to extraction for managing oral inflammation.

Area of Science:

  • Veterinary Medicine
  • Immunology
  • Oral Surgery

Background:

  • Gingivostomatitis (GS) presents diverse clinical patterns requiring varied treatments.
  • Immunomodulatory drugs, like cyclosporine, offer long-term benefits for GS by reducing immunologic triggers.
  • Refractory stomatitis in noncompliant animals presents significant management challenges.

Purpose of the Study:

  • To evaluate the efficacy of different therapeutic modalities for canine and feline gingivostomatitis.
  • To determine the viability of surgical extraction as a treatment for intractable stomatitis.
  • To explore combined immunomodulatory and surgical laser therapy as an alternative to extraction.

Main Methods:

  • Review of therapeutic options including antiviral therapy, steroids, laser fulguration, immunomodulation, and NSAIDs.

Related Experiment Videos

  • Assessment of whole-mouth or partial dental extraction in nonresponsive GS cases.
  • Evaluation of cyclosporine and carbon dioxide laser therapy for proliferative oral tissues.

    • Main Results:

    • Extraction led to oral inflammation resolution in approximately 70% of cats with chronic, severe oral disease, eliminating the need for further medication.
    • Cyclosporine demonstrated long-term benefits in reducing immunologic events contributing to GS.
    • Laser resection of proliferative tissue, combined with cyclosporine, is a viable alternative when extraction is not desired.

    Conclusions:

    • Dental extraction is a highly effective treatment for nonresponsive and painful stomatitis in cats and dogs.
    • Immunomodulation with cyclosporine and laser therapy provides a successful alternative to extraction.
    • Elimination of proliferative tissue and inflammation is key to achieving therapeutic success in GS management.