[Screening of the genes in controlling heart development of Drosophila]

It is becoming increasingly evident that remarkable similaries of heart development are revealed in Drosophila and vertebrate, therefore Drosophila can be used as a prototype to explore the vertebrate. This can in accelerate to revealing of the machanisms of human heart development. In order to screen and clone new genes that control the heart development,we have established the balanced-lethal lines by chemical mutagen and performed the heart-specific antibody. Ten of lines showed mutant phenotype,of which 6 were determined the smaller genetic sites for gene location.