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Mycoplasma pneumoniae infection in children with acute respiratory infection
Vijaya D Shenoy1, Santosh A Upadhyaya, Sugandhi P Rao
1Department of Pediatrics, Kasturba Medical College, Manipal, Karnataka, India. vijaypaed@yahoo.com
Insights
Mycoplasma pneumoniae infections were detected in 23.96% of pediatric inpatients with respiratory symptoms. Children aged 2-10 years showed the highest infection rates, often presenting with upper respiratory symptoms and cervical lymphadenopathy.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Mycoplasma pneumoniae is a common cause of respiratory infections in children.
- Accurate diagnosis is crucial for appropriate management and preventing complications.
Purpose of the Study:
- To determine the prevalence of IgM antibodies against Mycoplasma pneumoniae in hospitalized children with respiratory symptoms.
- To identify the clinical characteristics and age distribution of Mycoplasma pneumoniae infections.
Main Methods:
- A prospective study involving 93 pediatric inpatients with respiratory symptoms.
- Age-matched controls without respiratory illness were included.
- Detection of IgM antibodies against Mycoplasma pneumoniae using ELISA.
Main Results:
- 23.96% of inpatients tested positive for Mycoplasma pneumoniae IgM antibodies.
- The highest infection rates were observed in the 2-5 and 5-10 year age groups.
- Common presentation included upper respiratory symptoms and cervical lymphadenopathy; bronchial breathing was less frequent in positive cases.
Conclusions:
- Mycoplasma pneumoniae is a significant pathogen in pediatric respiratory infections.
- Early identification of Mycoplasma pneumoniae is important for this age group.
- Clinical presentation may vary, with less consolidation in Mycoplasma-positive patients.
Abstract:
A prospective study was performed on 93 children admitted to Kasturba Medical College Hospital, Manipal and TMA Pai Rotary Hospital of Udupi and Karkala. Blood samples from 93 children admitted to the ward with no respiratory illness were taken as age-matched controls for the inpatients, IgM antibody against Mycoplasma pneumoniae was detected using a commercial kit (Virion-Serion ELISA, Germany) following the manufacturer's instructions. 23.96% of the inpatients with respiratory tract symptoms had IgM antibodies against Mycoplasma pneumoniae. The highest infection rate was found to be in the 2-5 and 5-10 year age group. The most common mode of presentation was an upper respiratory focus of infection with cervical lymphadenopathy. Bronchial breathing signifying pneumonic consolidation was significantly less in the Mycoplasma positive group (p = 0.006). There was no statistically significant difference in the radiological findings in the Mycoplasma positive and Mycoplasma negative groups.
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