Projector 2: contig mapping for efficient gap-closure of prokaryotic genome sequence assemblies

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Sacha A F T van Hijum1, Aldert L Zomer, Oscar P Kuipers

  • 1Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, PO Box 14, 9750 AA Haren, The Netherlands.

Nucleic Acids Research
|June 28, 2005
PubMed

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Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.