Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The bioinformatics resource for oral pathogens.

Tsute Chen1, Kevin Abbey, Wen-jie Deng

  • 1The Forsyth Institute, 140 Fenway, Boston, MA 02115, USA. tchen@forsyth.org

Nucleic Acids Research
|June 28, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diabetes exacerbates experimental peri-implantitis in mice with elevated IL-17A-associated inflammation and IL-17F upregulation.

Scientific reports·2026
Same author

Pangenomes of the human oral microbiome.

Microbiology resource announcements·2026
Same author

Aging and periodontitis increase brain dissemination of oral bacteria.

Journal of periodontology·2026
Same author

Efficacy and Safety of Shenfu Injection in Patients with Septic Shock: A Randomized Controlled Open-Label Trial with Network Pharmacology-Based Mechanistic Insights.

Chinese journal of integrative medicine·2026
Same author

Vendor-specific microbiomes influence oral cancer development and its response to <i>Streptococcus mitis</i> intervention in mice.

Journal of oral microbiology·2026
Same author

Taxonomic Diversity and Clinical Correlations in Periapical Lesions by Next-Generation Sequencing Analysis.

Genes·2025
Same journal

Correction to 'New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress'.

Nucleic acids research·2026
Same journal

VeloRM: disentangling pre- and post-splicing RNA modification dynamics at single-cell resolution.

Nucleic acids research·2026
Same journal

Accessibility of telomeric overhangs to stabilizing small-molecule ligands.

Nucleic acids research·2026
Same journal

Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex.

Nucleic acids research·2026
Same journal

Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites.

Nucleic acids research·2026
Same journal

Correction to 'The Gene Ontology knowledgebase in 2026'.

Nucleic acids research·2026
See all related articles

The Bioinformatics Resource for Oral Pathogens (BROP) integrates diverse genomic data for oral pathogens, enabling easier comparison and analysis. This resource aids researchers in efficiently utilizing complex oral pathogen genomic information.

Area of Science:

  • Genomics
  • Bioinformatics
  • Oral Microbiology

Background:

  • Multiple annotated genome sequences exist for oral pathogens.
  • Inconsistent gene identification and annotation methods hinder data integration and analysis.

Purpose of the Study:

  • To develop an integrated bioinformatics resource for oral pathogens.
  • To facilitate data comparison, analysis, and data-mining of oral pathogen genomes.

Main Methods:

  • Integration of bioinformatics data from multiple sources.
  • Development of specialized software interfaces for data access and analysis.
  • Implementation of a graphical genome viewer for side-by-side comparison of annotated datasets.
  • Creation of automatic data-mining algorithms for up-to-date genome annotation.

Related Experiment Videos

  • Inclusion of comparative genomic tools like Genome-wide ORF Alignment (GOAL).

    • Main Results:

    • The Bioinformatics Resource for Oral Pathogens (BROP) provides integrated genomic data for oral pathogens.
    • BROP includes tools for visual genome comparison, automatic annotation updates, and comparative genomics.
    • The resource supports unfinished genomic sequences and offers flexible data access controls.

    Conclusions:

    • BROP offers a unified platform for accessing and analyzing oral pathogen genomic data.
    • The data integration and data-mining model of BROP can be extended to other organisms.
    • BROP enhances research efficiency by simplifying the use of diverse genomic datasets.