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Updated: Aug 17, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
[What are the markers of tobacco smoking?]
H Gourlain1, M Galliot-Guilley
1Laboratoire de Toxicologie Biologique, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75475 Paris Cedex 10. herve.gourlain@lrb.ap-hop-paris.fr
Abstract:
In this updated review of tobacco smoking markers (smokers non-smokers) in various biological environments, during varied circumstances of use, we present the parameters known to be detectable to date. The focus is placed on:--certain bio-markers used in routine practice: plasmatic, urinary or salivary cotinine end-expired carbon monoxide,--certain minor tobacco alkaloids such as anabasine and anatabine, as potential bio-markers, particularly for monitoring abstinence during nicotinic substitution therapy,-- use of superficial body growths (hair and nails) as a biological environment for measuring nicotine and cotinine to monitor exposure to environmental tobacco smoke and fetal exposure.
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